Subchronic Oral Dose Toxicity Study ofEnterococcus Faecalis2001 (EF 2001) in Mice

Subchronic Oral Dose Toxicity Study of Enterococcus Faecalis 2001 (EF 2001) in Mice

As a part of general toxicity studies of Enterococcus Faecalis 2001 (EF 2001) prepared using heat-treatment bacillus mort body EF 2001 in mice, this study examined the toxicity of EF 2001 in single and repeated administrations following the previous report in order to apply this product to preventive medicine. The safety of oral ingestion of EF 2001 was examined in 6-week-old male and female IC...

Thirteen-Week Study of PM014 Subchronic Oral Toxicity in Rats

PM014 is a modified herbal formula based on Chung-Sang-Bo-Ha-Tang, which is a well-known prescription drug used for curing various inflammatory pulmonary diseases. We previously showed that PM014 attenuated lung inflammation in a murine model of chronic obstructive pulmonary disease (COPD). The objective of the present study was to evaluate the chronic oral toxicity of PM014 in rats. PM014 was ...

Subchronic toxicity study of fixed dose combination of ceftriaxone-vancomycin in swiss albino mice

Antibiotics are highly successful in controlling bacterial infection but they have many toxic effects, sometimes very fatal. Aim of the present study was to evaluate subchronic toxicity of fixed dose combination of ceftriaxone-vancomycin in mice. Male and female mice were divided into four groups depending on dose of ceftraixone-vancomycin (0, 10, 100 and 500 mg/kg i.m.). Hematological, biochem...

Subchronic Oral Dose Toxicity of Freeze-dried Powder of Allomyrina dichotoma Larvae

The objective of this study was to investigate the toxicological information of freeze-dried powder from Allomyrina dichotoma (A. dichotoma) larvae as a food ingredient. The powder, suspended in distilled water, was administered once daily by oral gavage to four groups of Sprague-Dawley (SD) rats at dose levels of 0 (vehicle control), 250, 850, and 2500 mg/kg/day. After 13 wks of repeated admin...

Sub-chronic Oral Toxicity Test Repeated Dose 90 - Day Oral Toxicity Study in Non-rodents